Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435556 | 1.00 | NFE2L2 (0.53) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL9988820 | 0.78 | KDM4E (0.43) | KMT2AALDH1A1KDM4EPKMLMNA | |
| SCHEMBL2807525 | 0.76 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL4857575 | 0.76 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL2807530 | 0.76 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL3305717 | 0.73 | NFE2L2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL3305728 | 0.73 | NFE2L2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL3305722 | 0.73 | NFE2L2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL12513976 | 0.72 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3009380 | 0.72 | KDM4E (0.72) | ALDH1A1KDM4ELMNAMCL1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235923-A | Esters of 3-substituted-2-(aminocarbonyl)oxiranecarboxylic acids as lipogenesis inhibitors | SHELL OIL COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0018682-A1 | Oxiranecarboxylic acid ester derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |