Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | TRHR | P34981 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436794 | 0.89 | REN (0.54) | RENCTSDPLK1TRHR | |
| SCHEMBL11435645 | 0.85 | PSMB9 (0.44) | REN | |
| SCHEMBL11435639 | 0.85 | PSMB9 (0.44) | REN | |
| SCHEMBL17226098 | 0.82 | REN (0.61) | RENCTSDPLK1TRHR | |
| SCHEMBL11240079 | 0.80 | PSMB9 (0.52) | REN | |
| SCHEMBL11240100 | 0.80 | PSMB9 (0.52) | REN | |
| SCHEMBL7849192 | 0.80 | REN (0.65) | RENCTSDPLK1 | |
| SCHEMBL7852891 | 0.80 | REN (0.65) | RENCTSDPLK1 | |
| SCHEMBL7842935 | 0.80 | REN (0.65) | RENCTSDPLK1 | |
| SCHEMBL31435690 | 0.79 | REN (0.58) | RENCTSDTRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216209-A | Tripeptide angiotensin converting enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-08-05 | — | — | US | claimed |
| US-4216209-A | Tripeptide angiotensin converting enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |