Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | TRHR | P34981 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435650 | 0.89 | REN (0.56) | RENPLK1CTSDTRHR | |
| SCHEMBL11436783 | 0.85 | PSMB9 (0.43) | RENPLK1 | |
| SCHEMBL11436789 | 0.85 | PSMB9 (0.43) | RENPLK1 | |
| SCHEMBL17226098 | 0.81 | REN (0.61) | RENPLK1CTSDTRHR | |
| SCHEMBL7852891 | 0.79 | REN (0.65) | RENPLK1CTSD | |
| SCHEMBL7842935 | 0.79 | REN (0.65) | RENPLK1CTSD | |
| SCHEMBL7849192 | 0.79 | REN (0.65) | RENPLK1CTSD | |
| SCHEMBL13470161 | 0.78 | REN (0.56) | RENPLK1CTSDTRHR | |
| SCHEMBL31435690 | 0.77 | REN (0.58) | RENCTSDTRHR | |
| SCHEMBL23743861 | 0.76 | SLC15A2 (0.63) | RENTRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216209-A | Tripeptide angiotensin converting enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |