Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856515 | 0.80 | L3MBTL1 (0.46) | CNR1CNR2CASP1HSD17B10KDM4E | |
| SCHEMBL3656868 | 0.77 | KDM4E (0.44) | ALDH1A1CASP1HSD17B10KDM4EATM | |
| SCHEMBL16197311 | 0.75 | CNR2 (0.55) | CNR1CNR2CASP1HSD17B10L3MBTL1 | |
| SCHEMBL14697318 | 0.73 | NR3C2 (0.42) | CASP1HSD17B10KDM4EATML3MBTL1 | |
| SCHEMBL557886 | 0.73 | KDM4E (0.47) | CNR1CNR2CASP1HSD17B10KDM4E | |
| SCHEMBL9706894 | 0.73 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EATMKIF11MEN1 | |
| SCHEMBL22224651 | 0.72 | CASP1 (0.45) | CNR1CNR2CASP1HSD17B10KDM4E | |
| SCHEMBL8004519 | 0.72 | HSD17B10 (0.43) | ALDH1A1CASP1HSD17B10KDM4EATM | |
| SCHEMBL7767598 | 0.72 | HSD17B10 (0.43) | ALDH1A1CASP1HSD17B10KDM4EATM | |
| SCHEMBL7765366 | 0.71 | PDE4A (0.47) | ALDH1A1KDM4EMAPK1PDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186129-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-01-29 | — | — | US | disclosed |