SCHEMBL8909758

SCHEMBL8909758

C=CCS(=O)(=O)OC1CC(=O)NC1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114367 0.80 NPC1 (0.36) MAP3K14
SCHEMBL17065483 0.75 NPC1 (0.37) MAP3K14
SCHEMBL17065492 0.75 MAP3K14 (0.33) MAP3K14
SCHEMBL2573071 0.72 NPC1 (0.40)
SCHEMBL193688 0.72 MAP3K14 (0.39) MAP3K14
SCHEMBL1028530 0.72 MAP3K14 (0.39) MAP3K14
SCHEMBL29868031 0.71 CRBN (0.47)
SCHEMBL6272873 0.71 NPC1 (0.40)
SCHEMBL112502 0.71 NPC1 (0.40)
SCHEMBL5855515 0.68 MAP3K14 (0.39) MAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785465-A1 Molecular grafting of carboxyl reactive hardeners to energetically treated polyesters to promote adhesion of layers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1997-07-23 EP claimed
EP-0785465-A1 Molecular grafting of carboxyl reactive hardeners to energetically treated polyesters to promote adhesion of layers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1997-07-23 EP disclosed