SCHEMBL29868031

SCHEMBL29868031

O=C1CC(OS(=O)(=O)Cc2ccccc2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 10/20 0.47
KMT2A Q03164 2/20 0.42
DDB1 Q16531 6/20 0.40
HDAC8 Q9BY41 2/20 0.40
FAAH O00519 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
ELANE P08246 1/20 0.36
PRTN3 P24158 1/20 0.36
PRSS3 P35030 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
HTT P42858 1/20 0.35
CREBBP Q92793 2/20 0.34
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9437100 0.77 CRBN (0.43) CRBNKMT2ADDB1
SCHEMBL114367 0.76 NPC1 (0.36) CRBNDDB1CREBBPBRD4
SCHEMBL1929688 0.75 CRBN (0.44) CRBNDDB1HDAC8CREBBPBRD4
SCHEMBL17065483 0.72 NPC1 (0.37) CRBNKMT2ADDB1
SCHEMBL9656699 0.72 CRBN (0.46) CRBNDDB1HDAC8CA2CREBBP
SCHEMBL8909758 0.71 MAP3K14 (0.32)
SCHEMBL2573071 0.69 NPC1 (0.40) CRBNKMT2ADDB1FAAH
SCHEMBL193688 0.69 MAP3K14 (0.39) CRBNKMT2ADDB1
SCHEMBL148443 0.69 GPBAR1 (0.46) CRBNKMT2ADDB1CREBBPBRD4
SCHEMBL1028530 0.69 MAP3K14 (0.39) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022270640-A2 POLYMER COMPOUND, COSMETIC, AND THICKENER 富士フイルム和光純薬株式会社 2022-12-29 WO disclosed
WO-2022215283-A1 LAYERED FILM FOR PATTERN FORMATION, NON-PHOTOSENSITIVE SCREEN PRINTING PLATE, AND METHOD FOR MANUFACTURING SAME 株式会社 ムラカミ 2022-10-13 WO disclosed