Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112502 | 0.98 | NPC1 (0.40) | NPC1CRBNDDB1PRKCAALDH1A1 | |
| SCHEMBL6272873 | 0.98 | NPC1 (0.40) | NPC1CRBNDDB1PRKCAALDH1A1 | |
| SCHEMBL17065483 | 0.89 | NPC1 (0.37) | NPC1CRBNDDB1KMT2A | |
| SCHEMBL114367 | 0.84 | NPC1 (0.36) | NPC1CRBNDDB1LMNAMAPT | |
| SCHEMBL28153842 | 0.74 | NPC1 (0.48) | NPC1CRBNDDB1ALDH1A1L3MBTL1 | |
| SCHEMBL28311189 | 0.73 | PRKCA (0.38) | NPC1CRBNPRKCAALDH1A1L3MBTL1 | |
| SCHEMBL1028530 | 0.73 | MAP3K14 (0.39) | NPC1CRBNDDB1LMNAMAPT | |
| SCHEMBL27597851 | 0.73 | NPC1 (0.47) | NPC1CRBNDDB1ALDH1A1L3MBTL1 | |
| Methane SCHEMBL27666784 | 0.73 | NPC1 (0.47) | NPC1CRBNDDB1ALDH1A1L3MBTL1 | |
| SCHEMBL8909758 | 0.72 | MAP3K14 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384457-A2 | COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010055406-A2 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-05-20 | — | — | WO | disclosed |