Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450504 | 0.89 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11436721 | 0.89 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11446847 | 0.84 | MEN1 (0.41) | MEN1KMT2ATACR1SLC6A4KDM4E | |
| SCHEMBL11330943 | 0.81 | MEN1 (0.40) | MEN1KMT2ATACR1SLC6A4KDM4E | |
| SCHEMBL11450497 | 0.79 | MAPK1 (0.40) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11437571 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11446841 | 0.74 | SIGMAR1 (0.40) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11339656 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11437911 | 0.73 | RAB9A (0.37) | KMT2ANPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL11446547 | 0.73 | NPC1 (0.38) | MEN1KMT2AKDM4ENPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |