Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305846 | 0.92 | PGR (0.53) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL7596820 | 0.92 | PGR (0.61) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL11424742 | 0.86 | PGR (0.47) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL11433770 | 0.86 | PGR (0.46) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL11421774 | 0.82 | PGR (0.80) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL11421776 | 0.82 | PGR (0.80) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL7210548 | 0.82 | ABCB11 (0.62) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL7209821 | 0.81 | ABCB11 (0.59) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL11126579 | 0.81 | PGR (0.72) | PGRARNR3C1CYP3A4HIF1A | |
| SCHEMBL6859039 | 0.81 | CYP3A4 (0.61) | PGRARNR3C1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |