Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415799 | 0.83 | NHERF1 (0.46) | ALDH1A1MAPTIDH1MAPK1L3MBTL1 | |
| SCHEMBL11415802 | 0.83 | NFKBIA (0.52) | ALDH1A1MAPTIDH1MAPK1L3MBTL1 | |
| SCHEMBL11408919 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTCCR2PKMMAPK1 | |
| SCHEMBL11408921 | 0.82 | MAPT (0.45) | ALDH1A1MAPTCCR2PKMNSD2 | |
| SCHEMBL11438958 | 0.81 | NT5E (0.40) | ALDH1A1GAACASP6SMN1; SMN2HTT | |
| SCHEMBL11406040 | 0.79 | IDH1 (0.48) | MAPTPKMIDH1MAPK1L3MBTL1 | |
| SCHEMBL11405692 | 0.79 | IDH1 (0.42) | ALDH1A1MAPTPKMIDH1MAPK1 | |
| SCHEMBL11432314 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1MAPTIDH1MAPK1GAA | |
| SCHEMBL11412518 | 0.76 | NT5E (0.42) | ALDH1A1MAPTGAANSD2CASP6 | |
| SCHEMBL11412516 | 0.76 | NT5E (0.42) | ALDH1A1MAPTGAANSD2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229372-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4155931-A | COMPLEMENT INHIBITORS FOR MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |