Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CASP6 | P55212 | 4/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402861 | 0.94 | ALDH1A1 (0.40) | NT5EL3MBTL1CASP6NSD2DUSP3 | |
| SCHEMBL11412518 | 0.91 | NT5E (0.42) | NT5EL3MBTL1CASP6NSD2DUSP3 | |
| SCHEMBL11416600 | 0.87 | CASP6 (0.42) | L3MBTL1CASP6NSD2ALDH1A1MEN1 | |
| SCHEMBL11402862 | 0.85 | ALDH1A1 (0.43) | NT5EL3MBTL1CASP6ALDH1A1MEN1 | |
| SCHEMBL11432038 | 0.85 | CASP6 (0.40) | NT5EL3MBTL1CASP6NSD2ALDH1A1 | |
| SCHEMBL11411033 | 0.85 | TIMP3 (0.46) | NT5EL3MBTL1CASP6NSD2DUSP3 | |
| SCHEMBL11438958 | 0.84 | NT5E (0.40) | NT5ECASP6ALDH1A1MEN1KMT2A | |
| SCHEMBL11412735 | 0.83 | SLC40A1 (0.48) | NT5EL3MBTL1CASP6ALDH1A1MEN1 | |
| SCHEMBL11415799 | 0.82 | NHERF1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11440315 | 0.82 | POLB (0.41) | NT5EL3MBTL1CASP6NSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231958-A | AMINOPHENYLENECARBONYL /AND SULFONYL/IMINONAPHTHALENE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4229372-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4155931-A | COMPLEMENT INHIBITORS FOR MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |