Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 5/20 | 0.42 |
| ▸ | CASP6 | P55212 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | NSD2 | O96028 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437999 | 0.99 | RAPGEF4 (0.41) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11444032 | 0.85 | TIMP3 (0.49) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11427290 | 0.85 | TIMP3 (0.59) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11438340 | 0.85 | TIMP3 (0.54) | TIMP3CASP6ALDH1A1TDP1RECQL | |
| SCHEMBL11444030 | 0.84 | TIMP3 (0.48) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11425844 | 0.84 | TIMP3 (0.58) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11432539 | 0.83 | CASP6 (0.51) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11432315 | 0.83 | NT5E (0.51) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 | |
| SCHEMBL11437646 | 0.83 | CD40 (0.51) | TIMP3ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL11432307 | 0.82 | NT5E (0.50) | RAPGEF4TIMP3CASP6ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |