Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436078 | 0.88 | MAOB (0.42) | AHRMAOBTGFBR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11429371 | 0.86 | EGFR (0.44) | MAOBALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL11429789 | 0.86 | EGFR (0.44) | AHRHSD11B1MAOBALDH1A1MEN1 | |
| SCHEMBL11435056 | 0.85 | HSD11B1 (0.42) | AHRHSD11B1MEN1KMT2AALKBH3 | |
| SCHEMBL11433955 | 0.85 | MAOB (0.37) | HSD11B1MAOBRAB9ACYP3A4CYP2D6 | |
| SCHEMBL11439626 | 0.84 | ALKBH3 (0.43) | AHRHSD11B1MAOBPTGES2ALDH1A1 | |
| SCHEMBL11178194 | 0.84 | BRD4 (0.40) | MAOBALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL11437276 | 0.81 | ALDH1A1 (0.47) | MAOBALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL11436424 | 0.80 | RORB (0.44) | TGFBR1ALDH1A1MAPK14 | |
| SCHEMBL11428696 | 0.80 | HSD11B1 (0.50) | AHRHSD11B1PTGES2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |