Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421974 | 0.92 | KCNMA1 (0.47) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| SCHEMBL11431361 | 0.92 | ALDH1A1 (0.46) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| SCHEMBL11428788 | 0.84 | KCNMA1 (0.54) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| SCHEMBL11431960 | 0.84 | KCNMA1 (0.51) | KCNMA1ALDH1A1KMT2AHPGDNPC1 | |
| SCHEMBL11431132 | 0.84 | KCNMA1 (0.51) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| SCHEMBL11424108 | 0.84 | ALDH1A1 (0.46) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| SCHEMBL11438898 | 0.83 | ADORA3 (0.41) | ALDH1A1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL11432948 | 0.83 | KMT2A (0.40) | ALDH1A1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL11431176 | 0.82 | KCNMA1 (0.54) | KCNMA1ALDH1A1KMT2ATNFNOD1 | |
| Acetic Acid SCHEMBL11422162 | 0.82 | KCNMA1 (0.48) | KCNMA1ALDH1A1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |