Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432948 | 0.91 | KMT2A (0.40) | ADORA3KMT2AMEN1POLBGAA | |
| SCHEMBL11425752 | 0.91 | KMT2A (0.42) | ADORA3KMT2AMEN1POLBGAA | |
| SCHEMBL11425885 | 0.83 | KMT2A (0.41) | ADORA3KMT2AMEN1POLBGAA | |
| SCHEMBL11433572 | 0.83 | MPL (0.41) | ADORA3KMT2AMEN1POLBGAA | |
| SCHEMBL11439417 | 0.83 | MPL (0.46) | ADORA3KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL11439495 | 0.83 | KCNMA1 (0.47) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL11429460 | 0.82 | KMT2A (0.42) | ADORA3KMT2AMEN1POLBGAA | |
| SCHEMBL11431361 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL11436214 | 0.81 | RAB9A (0.41) | ADORA3KMT2AMEN1POLBGAA | |
| Acetic Acid SCHEMBL11425024 | 0.81 | MPL (0.43) | ADORA3KMT2AMEN1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |