Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167430 | 0.82 | ALOX15 (0.48) | CHRM2HTR1AADRA2ACHRM1SLC6A2 | |
| SCHEMBL7876579 | 0.81 | LMNA (0.47) | SLC6A2SLC6A4DRD3SLC6A3CYP1A2 | |
| SCHEMBL9292448 | 0.81 | MEN1 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8044031 | 0.80 | LMNA (0.47) | CHRM2HTR1AADRA2ACHRM1SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL9292400 | 0.80 | ALOX15 (0.47) | CHRM2HTR1AADRA2ACHRM1SLC6A2 | |
| SCHEMBL11429361 | 0.78 | NPSR1 (0.46) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9291592 | 0.77 | IDO1 (0.53) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9292651 | 0.77 | MEN1 (0.50) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL11192255 | 0.77 | ALDH1A1 (0.54) | CNR2ALDH1A1NPC1HPGDRAB9A | |
| Propane SCHEMBL10335665 | 0.76 | HTT (0.45) | CHRM2HTR1AADRA2ACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |