Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084593 | 0.83 | SLC6A2 (0.54) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL5960318 | 0.80 | ALDH1A1 (0.44) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL11094447 | 0.80 | MAPT (0.47) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL11093857 | 0.80 | LMNA (0.65) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL11095220 | 0.80 | HPGD (0.46) | POLBLMNAKMT2AHTTHPGD | |
| SCHEMBL11097216 | 0.79 | KMT2A (0.58) | LMNAKMT2AHTTHPGDALDH1A1 | |
| SCHEMBL11440099 | 0.79 | KDR (0.55) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL440880 | 0.78 | POLB (0.61) | POLBMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL11096087 | 0.78 | HPGD (0.47) | POLBLMNAKMT2AMAPTMEN1 | |
| SCHEMBL10869194 | 0.77 | SIRT1 (0.55) | POLBLMNAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018100-A2 | Substituted aromatic biologically active compound, a process for its preparation and its use as biocide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-29 | — | — | EP | disclosed |