SCHEMBL440880

SCHEMBL440880

N#CSc1ccccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 4/20 0.61
▸ CA12 O43570 2/20 0.53
▸ CA1 P00915 2/20 0.53
▸ CA2 P00918 2/20 0.53
▸ CA4 P22748 2/20 0.53
▸ CA7 P43166 2/20 0.53
▸ CA9 Q16790 2/20 0.53
▸ CYP1A2 P05177 1/20 0.52
▸ ALDH1A1 P00352 4/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ RAB9A P51151 3/20 0.47
▸ KDM4E B2RXH2 2/20 0.43
▸ HMGB1 P09429 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ CA6 P23280 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ NAPRT Q6XQN6 1/20 0.43
▸ CA14 Q9ULX7 1/20 0.43
▸ TDP1 Q9NUW8 2/20 0.42
▸ MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372011 0.85 POLB (0.48) POLBCA12CA1CA2CA4
SCHEMBL14744092 0.83 POLB (0.41) POLBCA12CA1CA2CA4
SCHEMBL28780147 0.83 AKR1C3 (0.50) POLBALDH1A1RAB9AKDM4ETDP1
SCHEMBL10869194 0.82 SIRT1 (0.55) POLBALDH1A1RAB9AKDM4EHPGD
SCHEMBL5960318 0.82 ALDH1A1 (0.44) POLBCA12CA1CA2CA4
SCHEMBL11093857 0.79 LMNA (0.65) POLBCA1CA2CA9ALDH1A1
SCHEMBL11084593 0.78 SLC6A2 (0.54) POLBHPGDTDP1MAPTGAA
SCHEMBL11440098 0.78 POLB (0.42) POLBALDH1A1HPGDSMN1; SMN2TDP1
SCHEMBL5330637 0.77 POLB (0.68) POLBCA12CA1CA2CA4
Hydrochloric Acid SCHEMBL11093147 0.77 IDO1 (0.47) POLBCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 — — CN claimed
CN-117342991-B Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新建材集团股份有限公司 2026-02-03 — — CN disclosed
US-20250051763-A1 METHODS AND SYSTEMS FOR CONDITIONALLY REGULATING GENE EXPRESSION FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD FOUNDATION (PT) 2025-02-13 — — US disclosed
CN-117342812-B Preparation method of slow-release enhanced cement grinding aid 华新水泥股份有限公司 2025-01-28 — — CN disclosed
US-20240084335-A1 CHIMERIC PROTEINS AND METHODS OF REGULATING GENE EXPRESSION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-03-14 — — US disclosed
CN-117342812-A Preparation method of slow-release enhanced cement grinding aid 华新水泥股份有限公司 2024-01-05 — — CN disclosed
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 — — CN disclosed
US-20230416336-A1 CHIMERIC PROTEINS AND METHODS OF IMMUNOTHERAPY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-12-28 — — US disclosed
US-11773411-B2 Chimeric proteins and methods of regulating gene expression THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-10-03 — — US disclosed
US-11655504-B2 High intensity labeled reactant compositions and methods for sequencing Quantum-Si Incorporated (US) 2023-05-23 — — US disclosed
EP-0892813-A1 RECOMBINANT PREPARATION OF CALCITONIN FRAGMENTS AND USE THEREOF IN THE PREPARATION OF CALCITONIN AND RELATED ANALOGS BIONEBRASKA, INC. (US) 1999-01-27 — — EP disclosed
EP-0796335-A1 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1997-09-24 — — EP disclosed
WO-1997029127-A1 RECOMBINANT PREPARATION OF CALCITONIN FRAGMENTS AND USE THEREOF IN THE PREPARATION OF CALCITONIN AND RELATED ANALOGS BIONEBRASKA, INC. (US) 1997-08-14 — — WO disclosed
WO-1996017942-A9 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS — 1996-08-15 — — WO disclosed
WO-1996017942-A1 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1996-06-13 — — WO disclosed
WO-1996017941-A2 PRODUCTION OF C-TERMINAL AMIDATED PEPTIDES FROM RECOMBINANT PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1996-06-13 — — WO disclosed
CN-1019667-B Process for preparing benzothiazinone derivatives SHELL INT RESEARCH (NL) 1992-12-30 — — CN disclosed
US-4833137-A FUNGICIDES FOR PLANTS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1989-05-23 — — US disclosed
CN-87104156-A Benzo buprofezin derivate — 1987-12-16 — — CN disclosed
EP-0245902-A2 Benzothiazinone derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-11-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655504-B2 High intensity labeled reactant compositions and methods for sequencing NSUN2, FBL, DNMT3A POLB 79/4885CA12 2287/4885CA1 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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