Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 13/20 | 0.40 |
| ▸ | BRAF | P15056 | 9/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435538 | 0.78 | EGFR (0.51) | KMT2AEGFRERBB4AURKALCK | |
| SCHEMBL850437 | 0.69 | HTT (0.62) | KMT2A | |
| SCHEMBL11428715 | 0.65 | RORC (0.37) | KDR | |
| SCHEMBL11433299 | 0.64 | MPO (0.48) | KMT2AEGFRERBB4KDR | |
| SCHEMBL31642971 | 0.64 | KMT2A (0.48) | KMT2A | |
| SCHEMBL11440590 | 0.63 | MAP2K1 (0.47) | KMT2AKDR | |
| SCHEMBL4238203 | 0.62 | PTPN1 (0.49) | KMT2A | |
| SCHEMBL4239432 | 0.62 | ALDH1A1 (0.51) | KMT2A | |
| SCHEMBL11433590 | 0.62 | MAPT (0.41) | KMT2AKDRBRAFEPHX2 | |
| SCHEMBL31396398 | 0.62 | ENPP3 (0.61) | KMT2ADHODHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181519-A | Diphenylamine derivative herbicides | SHELL OIL COMPANY (US) | 1980-01-01 | — | — | US | disclosed |