Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427396 | 0.86 | AKR1B1 (0.56) | AKR1B1SLC6A9POLBKDM4EAGBL2 | |
| SCHEMBL30733478 | 0.86 | AKR1B1 (0.62) | AKR1B1POLBKDM4ELMNAGAA | |
| SCHEMBL11551886 | 0.86 | AKR1B1 (0.62) | AKR1B1POLBKDM4ELMNAGAA | |
| SCHEMBL11759778 | 0.78 | SLC6A9 (0.48) | SLC6A9AGBL2CYP2C9HPGDCYP2C19 | |
| SCHEMBL11756825 | 0.77 | AGBL2 (0.55) | SLC6A9AGBL2CYP2C9HPGDCYP2C19 | |
| SCHEMBL11552428 | 0.77 | AKR1B1 (0.51) | AKR1B1POLBKDM4ELMNAGAA | |
| SCHEMBL4328724 | 0.75 | SLC6A9 (0.43) | SLC6A9POLBKDM4ELMNAHPGD | |
| SCHEMBL11430842 | 0.75 | MMP2 (0.63) | AKR1B1SLC6A9POLBKDM4ELMNA | |
| SCHEMBL10712007 | 0.73 | AGBL2 (0.44) | SLC6A9KDM4EAGBL2CYP2C9HPGD | |
| SCHEMBL11554657 | 0.73 | AKR1B1 (0.49) | AKR1B1SLC6A9POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |