Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551886 | 0.88 | AKR1B1 (0.62) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL30733478 | 0.88 | AKR1B1 (0.62) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL11442734 | 0.86 | AKR1B1 (0.53) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL11552428 | 0.85 | AKR1B1 (0.51) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL11430842 | 0.82 | MMP2 (0.63) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL11554657 | 0.80 | AKR1B1 (0.49) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL3640100 | 0.79 | CYP2C9 (0.72) | AKR1B1LMNACYP2C9HPGDCYP2C19 | |
| SCHEMBL11400370 | 0.77 | AKR1B1 (0.46) | AKR1B1POLBLMNAGAACYP2C9 | |
| SCHEMBL11759221 | 0.74 | AGBL2 (0.55) | AKR1B1CYP2C9HPGDCYP2C19AGBL2 | |
| SCHEMBL109215 | 0.74 | AKR1B1 (1.00) | AKR1B1LMNAGAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |