Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL8140462 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL11397241 | 0.84 | OGA (0.44) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL6517802 | 0.84 | TSHR (0.45) | ALDH1A1RAB9A | |
| Ribose (Furanose) SCHEMBL11407593 | 0.82 | PYGB (0.43) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL15321131 | 0.82 | PYGB (0.41) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL11356472 | 0.81 | SLC29A1 (0.42) | ALDH1A1SLC29A1 | |
| Ribose (Furanose) SCHEMBL18152615 | 0.81 | SLC29A1 (0.42) | ALDH1A1SLC29A1 | |
| Ribose (Furanose) SCHEMBL2325834 | 0.81 | LMNA (0.49) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL142622 | 0.81 | LMNA (0.49) | ALDH1A1LMNAMTORTHRBMDM2 | |
| Ribose (Furanose) SCHEMBL8833 | 0.81 | LMNA (0.49) | ALDH1A1LMNAMTORTHRBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210638-A | 5-TRIFLUOROMETHYL-2'-DEOXYCYCTIDINE AND TETRAHYDROURIDINE OR 2'-DEOXYTETRAHYDROURIDINE | PCR, INC. (US) | 1980-07-01 | — | — | US | disclosed |