Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL3341287 | 1.00 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL142622 | 1.00 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL8833 | 1.00 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL561196 | 0.99 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL628713 | 0.99 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL2990095 | 0.89 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL8611560 | 0.83 | LMNA (0.43) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytosine SCHEMBL16700148 | 0.83 | FBP1 (0.47) | — | |
| Cytosine SCHEMBL11321353 | 0.83 | FBP1 (0.47) | — | |
| Cytosine SCHEMBL1687124 | 0.82 | ALDH1A1 (0.44) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260601-A1 | Recombinant mutants of rhabdovirus and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-11-24 | — | — | US | claimed |
| EP-2353016-A1 | NON-HUMAN ANIMALS HAVING PSYCHIATRIC DISORDERS, METHOD FOR OBTAINING SAME, AND USE THEREOF FOR DRUG SCREENING | Université Henri Poincaré Nancy 1 (FR) | 2011-08-10 | — | — | EP | disclosed |
| US-20050260601-A1 | Recombinant mutants of rhabdovirus and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-11-24 | — | — | US | disclosed |
| WO-2005082860-A1 | TETRACYCLINES AND THEIR USE AS CALPAIN INHIBITORS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2005-09-09 | — | — | WO | disclosed |