Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478905 | 0.83 | PIK3CG (0.48) | PIK3CGKMOPIK3CAPIK3CBHDAC6 | |
| SCHEMBL11445170 | 0.83 | PIK3CG (0.61) | BCHEACHEPIK3CGPIK3CAPIK3CB | |
| SCHEMBL3252241 | 0.82 | PIK3CG (0.48) | BCHEPIK3CGADK | |
| Dimethylamine SCHEMBL11470117 | 0.80 | PIK3CG (0.44) | PIK3CGADK | |
| SCHEMBL11470380 | 0.74 | ADK (0.56) | PIK3CGKMOADK | |
| SCHEMBL11470116 | 0.73 | ADK (0.71) | PIK3CGADK | |
| SCHEMBL3422110 | 0.71 | IDO1 (0.58) | BCHEACHEKMOATRIDO1 | |
| SCHEMBL4413423 | 0.71 | BCHE (0.51) | BCHEACHEKMOATRIDO1 | |
| SCHEMBL9146709 | 0.70 | KDM4E (0.36) | PIK3CGADK | |
| SCHEMBL2126795 | 0.69 | KMO (0.67) | BCHEACHEPIK3CGKMOPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183934-A | NONALIURETIC DIURETICS | ABBOTT LABORATORIES (US) | 1980-01-15 | — | — | US | disclosed |