Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453386 | 0.87 | RAB9A (0.53) | KCNQ2KMT2AGAAPKMALDH1A1 | |
| SCHEMBL11446342 | 0.79 | SMN1; SMN2 (0.59) | KMT2AGAAALDH1A1TSHRLMNA | |
| SCHEMBL13167010 | 0.79 | KCNQ2 (1.00) | KCNQ2KMT2AGAAPKMALDH1A1 | |
| SCHEMBL11445874 | 0.79 | ALDH1A1 (0.64) | KMT2APKMALDH1A1LMNAMAPT | |
| SCHEMBL11445531 | 0.76 | ALDH1A1 (0.67) | KMT2AGAAPKMALDH1A1TSHR | |
| SCHEMBL10640396 | 0.75 | TP53 (0.53) | KMT2AGAAALDH1A1TSHRLMNA | |
| SCHEMBL11445291 | 0.75 | TSHR (0.52) | KCNQ2KMT2AGAAPKMALDH1A1 | |
| SCHEMBL8938751 | 0.75 | MAPT (0.47) | KMT2AGAAPKMALDH1A1TSHR | |
| SCHEMBL10623856 | 0.73 | KDM4E (0.58) | PKMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11446797 | 0.73 | ALDH1A1 (0.56) | KCNQ2KMT2AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186199-A | Indolo-,1,2-dihydroindolo-, and 1,2,6,7-tetrahydroindolo [1,7-ab][1,5] benzodiazepines | AMERICAN HOECHST CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |