Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623520 | 0.88 | MEN1 (0.43) | MAPTALDH1A1NOTUMUSP2MEN1 | |
| SCHEMBL11445874 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1NOTUMUSP2P2RY1 | |
| SCHEMBL11446342 | 0.78 | SMN1; SMN2 (0.59) | MAPTALDH1A1USP2MEN1KMT2A | |
| SCHEMBL14355836 | 0.78 | MAPK1 (0.60) | MAPTALDH1A1USP2MEN1KMT2A | |
| SCHEMBL10623856 | 0.78 | KDM4E (0.58) | MAPTALDH1A1USP2SMN1; SMN2NPC1 | |
| SCHEMBL11445291 | 0.77 | TSHR (0.52) | MAPTALDH1A1USP2P2RY1KMT2A | |
| SCHEMBL11446797 | 0.75 | ALDH1A1 (0.56) | ALDH1A1USP2P2RY1KMT2ASMN1; SMN2 | |
| SCHEMBL11445253 | 0.75 | KCNQ2 (0.65) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14356002 | 0.74 | CHEK1 (0.54) | MAPTPOLBGAA | |
| SCHEMBL11445341 | 0.74 | TSHR (0.62) | ALDH1A1USP2KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536717-A | ANTIDEPRESSANTS, ANALGESICS | HOECHST MARION ROUSSEL INC. (US) | 1996-07-16 | — | — | US | disclosed |