Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.55 |
| ▸ | QDPR | P09417 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444261 | 0.88 | QDPR (0.56) | MCHR1QDPRSIGMAR1ALDH1A1LMNA | |
| SCHEMBL31073538 | 0.85 | MCHR1 (0.53) | MCHR1SIGMAR1ALDH1A1LMNARAD52 | |
| SCHEMBL11562993 | 0.84 | DRD2 (0.49) | MCHR1SIGMAR1ALDH1A1LMNARAD52 | |
| SCHEMBL7287663 | 0.82 | QDPR (0.62) | MCHR1QDPRALDH1A1LMNA | |
| SCHEMBL31073611 | 0.81 | QDPR (0.52) | MCHR1QDPRLMNAHSD17B3 | |
| SCHEMBL7230489 | 0.80 | QDPR (0.60) | MCHR1QDPRALDH1A1 | |
| SCHEMBL11465783 | 0.80 | HAO1 (0.60) | ALDH1A1LMNARAD52SMN1; SMN2HSD17B3 | |
| SCHEMBL11444260 | 0.79 | QDPR (0.56) | MCHR1QDPRSMN1; SMN2NAMPT | |
| SCHEMBL31073554 | 0.79 | MGLL (0.65) | LMNA | |
| SCHEMBL11439049 | 0.79 | QDPR (0.59) | MCHR1QDPRSIGMAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188396-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |