Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934600 | 0.87 | ALDH1A1 (0.40) | CA1CA2KMT2AEPHX2FABP7 | |
| SCHEMBL1456494 | 0.82 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL8697389 | 0.80 | AKR1B1 (0.41) | PPIACYP1A2MAPT | |
| SCHEMBL5818114 | 0.79 | CA1 (0.33) | CA1CA2PPIACYP1A2 | |
| SCHEMBL5917355 | 0.77 | CA1 (0.32) | CA1CA2PPIACYP1A2CYP2D6 | |
| SCHEMBL7875378 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL2587914 | 0.76 | PPIA (0.40) | KMT2AFABP7FABP3FABP5PPIA | |
| SCHEMBL5488253 | 0.76 | CA1 (0.37) | CA1CA2PPIA | |
| SCHEMBL3165966 | 0.71 | TTR (0.35) | CA1CA2POLBPPIASMN1; SMN2 | |
| SCHEMBL45391 | 0.71 | HTR7 (0.36) | CA1CA2KMT2APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3325 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715346-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2024-01-03 | — | — | EP | claimed |
| EP-2970107-B1 | PHOTOSWITCHABLE HDAC INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| EP-3171874-B1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2020-11-18 | — | — | EP | claimed |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-8759516-B2 | Inhibitors of Bruton's tyrosine kinase | PHARMACYCLICS, INC. (US) | 2014-06-24 | — | — | US | claimed |
| US-20140039186-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2014-02-06 | — | — | US | claimed |
| US-20130304089-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | QUEST PHARMATECH INC. (CA) | 2013-11-14 | — | — | US | claimed |
| EP-0261283-B2 | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors and useful conjugates thereof | APPLIED BIOSYSTEMS (US) | 1995-04-19 | — | — | EP | claimed |
| US-5258538-A | 2,3-disubstituted-1,3,2-oxazaphosphacycloalkanes as nucleic acid linking agents | APPLIED BIOSYSTEMS, INC. (US) | 1993-11-02 | — | — | US | claimed |
| US-5212304-A | Amino-derivatized phosphoramidite linking agents | APPLIED BIOSYSTEMS, INC. (US) | 1993-05-18 | — | — | US | claimed |
| EP-0261283-A1 | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors and useful conjugates thereof | APPLIED BIOSYSTEMS, INC. (US) | 1988-03-30 | — | — | EP | claimed |
| WO-1988002004-A1 | AMINO-DERIVATIZED PHOSPHITE AND PHOSPHATE LINKING AGENTS, PHOSPHORAMIDITE PRECURSORS, AND USEFUL CONJUGATES | APPLIED BIOSYSTEMS, INC. (US) | 1988-03-24 | — | — | WO | claimed |