Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 2/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114462 | 0.87 | CA1 (0.35) | EPHX2KMT2ACA1CA2FABP7 | |
| SCHEMBL1456494 | 0.82 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL28430401 | 0.81 | ALDH1A1 (0.44) | ALDH1A1EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL8697389 | 0.80 | AKR1B1 (0.41) | PPIACYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL5818114 | 0.79 | CA1 (0.33) | CA1CA2PPIACYP1A2 | |
| SCHEMBL5917355 | 0.77 | CA1 (0.32) | CA1CA2PPIACYP1A2CYP2C19 | |
| SCHEMBL7875378 | 0.77 | SMN1; SMN2 (0.37) | ALDH1A1TSHRNPC1MAPTRAB9A | |
| SCHEMBL2587914 | 0.76 | PPIA (0.40) | ALDH1A1KMT2AFABP7FABP5FABP3 | |
| SCHEMBL8987674 | 0.76 | ALDH1A1 (0.40) | ALDH1A1EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL5488253 | 0.76 | CA1 (0.37) | CA1CA2PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761554-A2 | PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME | Biosource Pharm, Inc. (US) | 2007-03-14 | — | — | EP | claimed |
| WO-2006083317-A2 | PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME | BIOSOURCE PHARM, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-8889826-B2 | Peptide antibiotics and methods for making same | BIOSOURCE PHARM, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| EP-2332965-A1 | Peptide antibiotics and methods for making same | BioSource Pharm, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| EP-1337270-B1 | LONG-ACTING INTERFERON AND INTERLUKIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RES & DEV (IL) | 2008-07-16 | — | — | EP | disclosed |
| WO-2006083317-A9 | PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME | BIOSOURCE PHARM INC (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| EP-1337270-A4 | LONG-ACTING CYTOKINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RES & DEV (IL) | 2005-09-14 | — | — | EP | disclosed |
| US-20040131586-A1 | Long-acting cytokine derivatives and pharmaceutical compositions comprising them | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-07-08 | — | — | US | disclosed |
| EP-1337270-A2 | LONG-ACTING CYTOKINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002036067-A2 | LONG-ACTING CYTOKINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131586-A1 | Long-acting cytokine derivatives and pharmaceutical compositions comprising them | IL2, IFNG, CSF3R | ALDH1A1 1778/4885EPHX2 523/4885KMT2A 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.