Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456861 | 0.92 | MAPT (0.47) | MAPTTSHRHTTMEN1KMT2A | |
| SCHEMBL11457257 | 0.86 | DRD2 (0.45) | MAPTMEN1KMT2AGAARAD52 | |
| SCHEMBL11456862 | 0.86 | DRD2 (0.45) | MAPTTSHRMEN1KMT2AGAA | |
| SCHEMBL11448296 | 0.86 | DRD2 (0.45) | MAPTTSHRHTTMEN1KMT2A | |
| SCHEMBL11446922 | 0.85 | HTR2A (0.49) | MAPTTSHRMEN1KMT2ARAD52 | |
| SCHEMBL11446395 | 0.84 | DRD2 (0.49) | MAPTTSHRHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11446447 | 0.83 | DRD2 (0.48) | MAPTTSHRHTTMEN1KMT2A | |
| SCHEMBL11447188 | 0.83 | GFER (0.52) | TSHRMEN1KMT2AGAACCR3 | |
| SCHEMBL11446553 | 0.81 | DRD3 (0.52) | MAPTTSHRHTTMEN1KMT2A | |
| SCHEMBL11446283 | 0.80 | ADRA1D (0.49) | MAPTTSHRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |