Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457351 | 0.84 | HPGD (0.39) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11446810 | 0.81 | BDKRB2 (0.43) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11370074 | 0.80 | HPGD (0.39) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11809650 | 0.80 | CXCL8 (0.43) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17486805 | 0.78 | BDKRB2 (0.49) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7684987 | 0.78 | PTGS1 (0.57) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11814111 | 0.76 | ALDH1A1 (0.47) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7674645 | 0.76 | PGR (0.46) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11448426 | 0.76 | CXCL8 (0.62) | HPGDALDH1A1LMNAKDM4EPTGS1 | |
| SCHEMBL17486809 | 0.75 | BDKRB2 (0.47) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200645-A | ANTIINFLAMMATORY | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| US-4200645-A | ANTIINFLAMMATORY | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | disclosed |