Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440496 | 0.85 | LMNA (0.46) | LMNAMAPTNPSR1HTTKMT2A | |
| SCHEMBL5952426 | 0.78 | ALDH1A1 (0.59) | LMNAMAPTHTTKMT2AALDH1A1 | |
| SCHEMBL11435140 | 0.76 | KMT2A (0.42) | LMNAMAPTNPSR1HTTKMT2A | |
| SCHEMBL13180237 | 0.76 | KMT2A (0.50) | LMNAMAPTNPSR1HTTKMT2A | |
| SCHEMBL11435281 | 0.74 | HTT (0.40) | LMNAMAPTNPSR1HTTKMT2A | |
| SCHEMBL28797218 | 0.74 | SMN1; SMN2 (0.50) | LMNANPSR1HTTKMT2AALDH1A1 | |
| SCHEMBL11439258 | 0.73 | TDP1 (0.47) | LMNAMAPTKMT2ATP53SMN1; SMN2 | |
| SCHEMBL11433388 | 0.72 | RORC (0.49) | NPSR1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11442327 | 0.71 | RORC (0.45) | LMNAMAPTKMT2AALDH1A1TP53 | |
| SCHEMBL14452372 | 0.70 | L3MBTL1 (0.61) | LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199347-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |