Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 12/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455721 | 0.95 | LTA4H (0.48) | LTA4HKDM4EHRH3 | |
| SCHEMBL11449154 | 0.88 | LTA4H (0.50) | LTA4HKDM4ECHEK2 | |
| SCHEMBL11448671 | 0.85 | LTA4H (0.68) | LTA4HCHEK2 | |
| SCHEMBL6608869 | 0.85 | LTA4H (0.68) | LTA4HCHEK2 | |
| SCHEMBL6600614 | 0.85 | NFE2L2 (0.60) | LTA4HCHEK2 | |
| SCHEMBL11447913 | 0.85 | LTA4H (0.50) | LTA4HKDM4ECHEK2 | |
| SCHEMBL7817605 | 0.85 | LTA4H (0.50) | LTA4HCHEK2 | |
| SCHEMBL2185418 | 0.85 | LTA4H (0.50) | LTA4HCHEK2 | |
| SCHEMBL4965391 | 0.84 | LTA4H (0.64) | LTA4H | |
| SCHEMBL16313564 | 0.84 | LTA4H (0.68) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |