Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548845 | 0.96 | KDM4E (0.44) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11465317 | 0.89 | MLYCD (0.40) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11465583 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11552261 | 0.86 | NPC1 (0.41) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11550585 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11446669 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2AKDM4ENPC1MITF | |
| Ethylbenzene SCHEMBL11595377 | 0.80 | L3MBTL1 (0.39) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11332192 | 0.80 | KDM4E (0.47) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11550110 | 0.79 | MEN1 (0.41) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11548568 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AKDM4ENPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |