Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550585 | 0.96 | ALDH1A1 (0.50) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11548568 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11547947 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11446729 | 0.89 | BCL2A1 (0.37) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11448180 | 0.88 | MEN1 (0.42) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| Ethylbenzene SCHEMBL11570518 | 0.87 | AGER (0.38) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11547950 | 0.85 | NPC1 (0.38) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11465317 | 0.84 | MLYCD (0.40) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| Ethylbenzene SCHEMBL11337300 | 0.84 | AGER (0.40) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11548845 | 0.84 | KDM4E (0.44) | ALDH1A1MITFSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |