SCHEMBL11448337

SCHEMBL11448337

CC(C)N(C(=O)c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.51
ADAMTS5 Q9UNA0 2/20 0.49
TP53 P04637 2/20 0.49
MAPT P10636 1/20 0.49
FLT1 P17948 1/20 0.48
FLT4 P35916 1/20 0.48
KDR P35968 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA3 P07451 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11836506 0.74 HSD11B1 (0.53) HSD11B1TP53MAPTFLT1FLT4
SCHEMBL10915389 0.74 HSD11B1 (0.47) HSD11B1TP53MAPTL3MBTL1CA12
SCHEMBL5899459 0.73 PGR (0.52) ADAMTS5TP53FLT1FLT4KDR
SCHEMBL9772300 0.72 FLT1 (0.50) HSD11B1MAPTFLT1FLT4KDR
SCHEMBL5899593 0.72 KMT2A (0.54) HSD11B1ADAMTS5MAPTCA12CA1
SCHEMBL27550108 0.70 KMT2A (0.47) HSD11B1MAPTKMT2AKEAP1NFE2L2
SCHEMBL10710904 0.70 FLT1 (0.48) HSD11B1MAPTFLT1FLT4KDR
SCHEMBL10281161 0.70 ALDH1A1 (0.55) ADAMTS5MAPTCA12CA1CA2
Benzoic Acid SCHEMBL27807346 0.69 PTGS2 (0.63) FLT1FLT4KDRL3MBTL1TAS2R14
SCHEMBL2332262 0.69 SMN1; SMN2 (0.59) MAPTCA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4233061-A PREEMERGENCE HERBICIDES FOR USE IN RICE PADDIES UTSUNOMIYA UNIVERSITY (JP) 1980-11-11 US disclosed
US-4157257-A HERBICIDES FOR APPLICATION TO AQUATIC RICE PADDIES UTSUNOMIYA UNIVERSITY (JP) 1979-06-05 US disclosed