Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466693 | 0.96 | GHSR (0.48) | GHSRLTA4HSLC6A2SLC6A4 | |
| SCHEMBL11456280 | 0.89 | GHSR (0.52) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11448946 | 0.88 | LTA4H (0.51) | GHSRLTA4HPOLB | |
| SCHEMBL11449265 | 0.87 | SLC6A3 (0.48) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11448239 | 0.87 | LTA4H (0.46) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11450652 | 0.85 | LTA4H (0.41) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11456857 | 0.84 | LTA4H (0.46) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11447961 | 0.84 | LTA4H (0.46) | GHSRLTA4HSLC6A4POLB | |
| SCHEMBL11447773 | 0.84 | LTA4H (0.51) | GHSRLTA4HSLC6A2SLC6A4POLB | |
| SCHEMBL11455787 | 0.84 | LTA4H (0.51) | LTA4HSLC6A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |