Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773970 | 0.81 | HDAC3 (0.58) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL10465722 | 0.81 | GSK3B (0.53) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL11074836 | 0.81 | GSK3B (0.53) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL1282 | 0.80 | MAPT (0.52) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL11806422 | 0.79 | NPC1 (0.59) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL2064455 | 0.78 | NPC1 (0.58) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL3641682 | 0.78 | GSK3B (0.57) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL13606921 | 0.74 | NPC1 (0.54) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL4549475 | 0.74 | RAB9A (0.64) | NPC1RAB9AALDH1A1MAPTGSK3B | |
| SCHEMBL17702639 | 0.73 | NPC1 (0.53) | NPC1RAB9AALDH1A1MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214094-A | ANTILIPEMIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |