Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GPX4 | P36969 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436576 | 0.80 | ANPEP (0.38) | ALDH1A1TP53 | |
| SCHEMBL11443012 | 0.75 | TP53 (0.36) | HPGDTDP1KMT2AALDH1A1HTT | |
| SCHEMBL11450853 | 0.73 | FAAH (0.41) | — | |
| SCHEMBL22852718 | 0.73 | TERT (0.47) | TERTHPGDTDP1NPC1RAB9A | |
| SCHEMBL11688270 | 0.69 | TERT (0.49) | TERTKMT2ASCN2ARECQLL3MBTL1 | |
| SCHEMBL8538425 | 0.68 | TERT (0.48) | TERTHPGDNPC1RAB9AKMT2A | |
| SCHEMBL22181066 | 0.67 | TERT (0.50) | TERTHPGDKMT2AALDH1A1SCN2A | |
| SCHEMBL13415413 | 0.66 | TERT (0.54) | TERTHPGDTDP1NPC1RAB9A | |
| SCHEMBL2860049 | 0.66 | PARP1 (0.52) | TERTHPGDRAB9AALDH1A1SCN2A | |
| SCHEMBL11443127 | 0.65 | KMT2A (0.37) | KMT2AALDH1A1TP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213915-A | FUNGICIDES, NEMATOCIDES | PPG INDUSTRIES, INC. (US) | 1980-07-22 | — | — | US | disclosed |