Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437135 | 0.75 | ALDH1A1 (0.35) | TP53EGFRERBB2MAPTALDH1A1 | |
| SCHEMBL11450853 | 0.75 | FAAH (0.41) | LMNATSHR | |
| SCHEMBL11450855 | 0.75 | TERT (0.40) | TP53MAPTHPGDALDH1A1HTT | |
| SCHEMBL11436576 | 0.70 | ANPEP (0.38) | TP53ALDH1A1LMNA | |
| SCHEMBL9725704 | 0.69 | TP53 (0.56) | TP53PKMALDH1A1HTTKMT2A | |
| SCHEMBL11450845 | 0.68 | HDAC4 (0.40) | HPGDPKMALDH1A1GAATSHR | |
| SCHEMBL11443127 | 0.67 | KMT2A (0.37) | TP53MAPTPKMALDH1A1KMT2A | |
| SCHEMBL11443113 | 0.67 | ACHE (0.36) | MAPT | |
| SCHEMBL11436597 | 0.65 | ACHE (0.36) | TP53PKM | |
| SCHEMBL11770708 | 0.63 | TP53 (0.49) | TP53ALDH1A1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213915-A | FUNGICIDES, NEMATOCIDES | PPG INDUSTRIES, INC. (US) | 1980-07-22 | — | — | US | disclosed |