Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | PDE1A | P54750 | 2/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.51 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452542 | 0.91 | HTT (0.59) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL10408838 | 0.87 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL11463803 | 0.84 | HTT (0.56) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL11452052 | 0.83 | HTT (0.67) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL11017458 | 0.82 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL11462599 | 0.79 | SMN1; SMN2 (0.84) | PDE4APDE4BPDE4CPDE4DHTT | |
| Arprinocid SCHEMBL31025603 | 0.78 | ADORA2A (0.60) | HTTLMNASMN1; SMN2ADORA2AADORA1 | |
| Arprinocid SCHEMBL31379008 | 0.78 | ADORA2A (0.60) | HTTLMNASMN1; SMN2ADORA2AADORA1 | |
| Arprinocid SCHEMBL8375355 | 0.78 | ADORA2A (0.60) | HTTLMNASMN1; SMN2ADORA2AADORA1 | |
| Arprinocid SCHEMBL126655 | 0.78 | ADORA2A (0.60) | HTTLMNASMN1; SMN2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189485-A | ANTICOCCIDIAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | claimed |
| US-4189485-A | ANTICOCCIDIAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |