Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475288 | 0.98 | DPP4 (0.46) | DPP4LTA4HALDH1A1KDM4ERAB9A | |
| SCHEMBL1253872 | 0.87 | — | — | |
| SCHEMBL1992492 | 0.85 | — | — | |
| SCHEMBL275321 | 0.78 | HDAC3 (0.36) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL5915087 | 0.78 | HDAC3 (0.36) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL30449321 | 0.78 | CYP1A1 (0.34) | — | |
| SCHEMBL590270 | 0.78 | CYP2E1 (0.40) | ALDH1A1KDM4ERAB9ANPC1HPGD | |
| SCHEMBL591209 | 0.77 | — | — | |
| SCHEMBL27983971 | 0.77 | CYP1A1 (0.32) | — | |
| SCHEMBL14889184 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053675-B | Benzene-methyl-bithiophene derivative and preparation method and application thereof | 浙江工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-109053675-A | A kind of benzene-methyl-bigeminy thiophene derivant and the preparation method and application thereof | 浙江工业大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108997405-A | A kind of silicon-phenyl-bigeminy thiophene derivant and the preparation method and application thereof | 浙江工业大学 | 2018-12-14 | — | — | CN | claimed |
| US-11603431-B2 | Organic semiconductors | Raynergy Tek Incorporation (TW) | 2023-03-14 | — | — | US | disclosed |
| EP-3411374-B9 | [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS | RAYNERGY TEK INC (TW) | 2023-01-11 | — | — | EP | disclosed |
| EP-3411374-B1 | [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS | RAYNERGY TEK INC (TW) | 2022-08-10 | — | — | EP | disclosed |
| CN-109053675-B | Benzene-methyl-bithiophene derivative and preparation method and application thereof | 浙江工业大学 | 2020-10-09 | — | — | CN | disclosed |
| US-20190040188-A1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | US | disclosed |
| CN-109053675-A | A kind of benzene-methyl-bigeminy thiophene derivant and the preparation method and application thereof | 浙江工业大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109020948-A | A kind of benzene-bigeminy thiophene derivant and the preparation method and application thereof | 浙江工业大学 | 2018-12-18 | — | — | CN | disclosed |
| CN-108997405-A | A kind of silicon-phenyl-bigeminy thiophene derivant and the preparation method and application thereof | 浙江工业大学 | 2018-12-14 | — | — | CN | disclosed |
| US-6184540-B1 | SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION | U.S. PHILIPS CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-1007035-A4 | POLYTHIOPHENE ANTI-TUMOR AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2000-11-22 | — | — | EP | disclosed |
| US-6124475-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| EP-1007035-A1 | POLYTHIOPHENE ANTI-TUMOR AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5919951-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0867437-A1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | Koninklijke Philips Electronics N.V. (NL) | 1998-09-30 | — | — | EP | disclosed |
| WO-1998023269-A1 | POLYTHIOPHENE ANTI-TUMOR AGENTS | PURDUE RESEARCH FOUNDATION (US) | 1998-06-04 | — | — | WO | disclosed |
| US-5741811-A | ADMINISTERING TO CANCER PATIENTS | PURDUE RESEARCH FOUNDATION (US) | 1998-04-21 | — | — | US | disclosed |
| US-5578636-A | Polythiophene anti-tumor agents | PURDUE RESEARCH FOUNDATION (US) | 1996-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040188-A1 | ORGANIC SEMICONDUCTORS | OCIAD2, OCIAD1, PPOX | DPP4 2006/4885LTA4H 2527/4885ALDH1A1 1558/4885 |
| US-11603431-B2 | Organic semiconductors | OCIAD2, OCIAD1, PPOX | DPP4 2006/4885LTA4H 2527/4885ALDH1A1 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.