Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145183 | 0.98 | DPP4 (0.43) | DPP4LTA4HALDH1A1KDM4ERAB9A | |
| SCHEMBL1992492 | 0.87 | — | — | |
| SCHEMBL1253872 | 0.85 | — | — | |
| SCHEMBL30449321 | 0.80 | CYP1A1 (0.34) | — | |
| SCHEMBL5915087 | 0.77 | HDAC3 (0.36) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL275321 | 0.77 | HDAC3 (0.36) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL590270 | 0.76 | CYP2E1 (0.40) | ALDH1A1KDM4ERAB9ANPC1HPGD | |
| SCHEMBL591209 | 0.76 | — | — | |
| SCHEMBL27983971 | 0.76 | CYP1A1 (0.32) | — | |
| SCHEMBL14889184 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487180-B1 | NOVEL ARTIFICIAL FLUORESCENT BASES | RIKEN (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-8895712-B2 | Artificial base pair capable of forming specific base pair | RIKEN (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20120245340-A1 | NOVEL ARTIFICIAL FLUORESCENT BASES | TAGCYX BIOTECHNOLOGIES (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120231462-A1 | ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR | TAGCYX BIOTECHNOLOGIES (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2487181-A1 | ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR | Riken (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2487180-A1 | NOVEL ARTIFICIAL FLUORESCENT BASES | Riken (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-0867437-B1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | KONINKL PHILIPS ELECTRONICS NV (NL) | 2002-11-13 | — | — | EP | disclosed |
| US-6184540-B1 | SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION | U.S. PHILIPS CORPORATION | 2001-02-06 | — | — | US | disclosed |
| US-6124475-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-5919951-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0867437-A1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | Koninklijke Philips Electronics N.V. (NL) | 1998-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231462-A1 | ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR | NSUN2, EIF2AK2, NSUN3 | DPP4 2281/4885LTA4H 4641/4885ALDH1A1 1963/4885 |
| US-20120245340-A1 | NOVEL ARTIFICIAL FLUORESCENT BASES | NUDT1, NT5C3B, NSUN2 | DPP4 826/4885LTA4H 3064/4885ALDH1A1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.