Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024486 | 0.86 | LMNA (0.49) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| SCHEMBL22408944 | 0.84 | ALDH1A1 (0.47) | S1PR4LMNARAB9ACYP3A4ALDH1A1 | |
| SCHEMBL11294647 | 0.83 | CA9 (0.59) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| SCHEMBL11595542 | 0.82 | CA1 (0.52) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| SCHEMBL11068177 | 0.82 | ALDH1A1 (0.48) | S1PR4LMNARAB9ATDP1ALDH1A1 | |
| SCHEMBL11675997 | 0.81 | S1PR4 (0.58) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| SCHEMBL9748282 | 0.80 | CYP3A4 (0.49) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| SCHEMBL11773684 | 0.80 | MAPK1 (0.47) | S1PR4LMNARAB9ATDP1ALDH1A1 | |
| SCHEMBL11676296 | 0.79 | POLB (0.49) | S1PR4LMNARAB9ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL10892666 | 0.79 | ALOX15 (0.50) | S1PR4LMNARAB9ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217271-A | Basic azo dyestuffs containing a n-picolinium alkylene amino phenyl group | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-08-12 | — | — | US | disclosed |
| US-4160643-A | FOR POLYMERS OF ACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |
| US-4153413-A | DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
| US-4134723-A | DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-01-16 | — | — | US | disclosed |