Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454101 | 0.88 | LMNA (0.35) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL18485447 | 0.76 | P2RX4 (0.50) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL11453040 | 0.68 | MEN1 (0.36) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL18485414 | 0.67 | L3MBTL1 (0.54) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL21855119 | 0.67 | CA12 (0.52) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL22649524 | 0.66 | CYP1A2 (0.40) | LMNACES1CA12CA9ALDH1A1 | |
| SCHEMBL11454100 | 0.66 | CASP1 (0.35) | ASAH1CA12CA9ALDH1A1MEN1 | |
| SCHEMBL9592299 | 0.66 | CA12 (0.47) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL887161 | 0.66 | CES1 (0.62) | LMNAASAH1CES1CA12CA9 | |
| SCHEMBL11419561 | 0.65 | RAB9A (0.50) | ASAH1CES1CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228178-A | Combating fungi with novel N-sulphenylated carbamoyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-14 | — | — | US | claimed |
| US-4228178-A | Combating fungi with novel N-sulphenylated carbamoyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-14 | — | — | US | disclosed |