Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341302 | 0.92 | ALDH1A1 (0.38) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11571012 | 0.88 | LTB4R2 (0.41) | LTB4R2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11572452 | 0.87 | LTB4R2 (0.34) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11465401 | 0.85 | ALDH1A1 (0.43) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11337740 | 0.84 | ALDH1A1 (0.41) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11450445 | 0.83 | TP53 (0.36) | LTB4R2SMN1; SMN2TP53PTGDR2OPRM1 | |
| SCHEMBL11330424 | 0.82 | SLC18A3 (0.43) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11350705 | 0.81 | ALDH1A1 (0.45) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11346998 | 0.80 | KDM4E (0.34) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11437590 | 0.78 | MEN1 (0.43) | LTB4R2SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4157398-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4156733-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |