Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454736 | 0.83 | LTB4R2 (0.38) | TP53LTB4R2OPRM1PTGDR2SMN1; SMN2 | |
| SCHEMBL11571012 | 0.78 | LTB4R2 (0.41) | LTB4R2OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL11572452 | 0.77 | LTB4R2 (0.34) | LTB4R2SMN1; SMN2TSHRSIGMAR1 | |
| SCHEMBL11341302 | 0.76 | ALDH1A1 (0.38) | LTB4R2OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL11330424 | 0.73 | SLC18A3 (0.43) | LTB4R2OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL11450446 | 0.72 | POLB (0.45) | OPRM1TSHRMAPTSIGMAR1 | |
| SCHEMBL11346998 | 0.72 | KDM4E (0.34) | LTB4R2OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL11465401 | 0.71 | ALDH1A1 (0.43) | LTB4R2OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL11437590 | 0.71 | MEN1 (0.43) | LTB4R2OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL11350705 | 0.70 | ALDH1A1 (0.45) | LTB4R2OPRM1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |