Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330424 | 0.94 | SLC18A3 (0.43) | LTB4R2SLC18A3NPC1RAB9ACHRM2 | |
| SCHEMBL11454736 | 0.88 | LTB4R2 (0.38) | LTB4R2NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL11572452 | 0.86 | LTB4R2 (0.34) | LTB4R2NPC1RAB9AKMT2ATSHR | |
| SCHEMBL11341302 | 0.83 | ALDH1A1 (0.38) | LTB4R2NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL11346998 | 0.82 | KDM4E (0.34) | LTB4R2SLC18A3NPC1RAB9AKMT2A | |
| SCHEMBL11571013 | 0.80 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM3CHRM1MAPK1 | |
| SCHEMBL11450445 | 0.78 | TP53 (0.36) | LTB4R2TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL11569471 | 0.77 | SLC18A3 (0.41) | SLC18A3NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL11330427 | 0.77 | SLC18A3 (0.46) | SLC18A3CHRM2CHRM3MAPK1OPRM1 | |
| SCHEMBL11595372 | 0.76 | SLC18A3 (0.50) | SLC18A3CHRM2CHRM3CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |