Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467866 | 0.83 | SMN1; SMN2 (0.52) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11459473 | 0.81 | KMT2A (0.48) | KMT2AMTNR1BMTNR1AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11457241 | 0.77 | DRD1 (0.52) | KMT2ADRD2DRD4DRD1CYP26A1 | |
| SCHEMBL7838664 | 0.72 | KDM4E (0.56) | KMT2ADRD2DRD4DRD1KDM4E | |
| SCHEMBL11459474 | 0.71 | MAPK1 (0.52) | DRD2DRD4DRD1MTNR1BMTNR1A | |
| SCHEMBL30468516 | 0.71 | ESR2 (0.47) | DRD2DRD4DRD1MTNR1BMTNR1A | |
| Hydrochloric Acid SCHEMBL11457319 | 0.69 | DRD2 (0.54) | DRD2DRD4DRD1DRD5DRD3 | |
| SCHEMBL11456231 | 0.68 | DRD2 (0.48) | DRD2DRD4DRD1DRD5DRD3 | |
| SCHEMBL11455526 | 0.68 | KMT2A (0.66) | KMT2ADRD2DRD4DRD1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11457812 | 0.67 | HRH3 (0.46) | DRD2DRD4DRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |