Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459473 | 0.92 | KMT2A (0.48) | SMN1; SMN2MAPTRAB9APARP1POLB | |
| SCHEMBL11455786 | 0.83 | KMT2A (0.50) | SMN1; SMN2MAPTRAB9APARP1KMT2A | |
| SCHEMBL30468516 | 0.75 | ESR2 (0.47) | ALDH1A1KDM4EHDAC1HDAC6LMNA | |
| SCHEMBL10660245 | 0.74 | KMT2A (0.55) | SMN1; SMN2MAPTPARP1POLBKMT2A | |
| SCHEMBL11455526 | 0.74 | KMT2A (0.66) | SMN1; SMN2MAPTRAB9AKMT2AABCB1 | |
| Hydrochloric Acid SCHEMBL11457319 | 0.72 | DRD2 (0.54) | — | |
| SCHEMBL11456231 | 0.72 | DRD2 (0.48) | — | |
| SCHEMBL26126968 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL26122057 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL11947276 | 0.71 | ABCB1 (0.69) | SMN1; SMN2MAPTRAB9AKMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |